- Hank Aaron, baseball Hall of Famer
- Willie Banks, Olympian and former world record-holder (Eagle Scout, Class of 1971)
- Bill Bradley, former basketball player for the New York Knicks and Hall of Famer (Eagle Scout, Class of 1957)
- Chan Gailey, former head coach of the Dallas Cowboys and Buffalo Bills (Eagle Scout, Class of 1966)
- Don Garlits, engineer who is considered the father of drag racing (Eagle Scout, Class of 1946)
- Pat Gillick, retired professional baseball executive and Hall of Famer (Eagle Scout, Class of 1951)
- Josh Hart, basketball player for the Portland Trail Blazers (Eagle Scout, Class of 2013)
- Steven Holcomb, gold medalist in bobsled at 2010 Winter Olympics (Eagle Scout, Class of 1995)
- Michael Jordan, former NBA player and current NBA team owner
- Tommy Lasorda, former baseball manager and Hall of Famer
- Ewing Kauffman, former owner of the Kansas City Royals and the man after whom their stadium is named (Eagle Scout, Class of 1931)
- Ray Malavasi, former head coach of the Denver Broncos and the Los Angeles Rams (Eagle Scout, Class of 1944)
- Peter McLoughlin, former president of the Seattle Seahawks (Eagle Scout, Class of 1971)
- Emery Moorehead, former tight end who won Super Bowl XX with the Chicago Bears (Eagle Scout, Class of 1969)
- Jim Mora, former head coach of the New Orleans Saints and Indianapolis Colts (Eagle Scout, Class of 1950)
- Nolan Ryan, former MLB pitcher and current Houston Astros executive
- Daniel Sorensen, Super Bowl-winning defensive back for the Kansas City Chiefs, later played for the New Orleans Saints (Eagle Scout, Class of 2008)
- Mark Spitz, gold medal-winning Olympic swimmer
- Joe Theismann, former NFL quarterback
- Shane Victorino, former pro baseball outfielder who won three Gold Gloves (Eagle Scout, Class of 1996)
- Ken Whisenhunt, former head coach of Arizona Cardinals and Tennessee Titans (Eagle Scout, Class of 1976)
- Steve Young, former NFL quarterback and sports broadcaster